For nearly two decades, the leading signs on hormone therapy were based on findings from observational studies such as the Nurses' Health Study. In 1985, researchers at Nurses' Health Study supported that postmenopausal women who took estrogen had lower rates of heart disease than women who had by no means taken the hormone. These conclusions were powerful and helped drive the upsurge in hormone prescriptions in the 1980s and 1990s. Nevertheless in 2002, in a spectacular turnaround, researchers for a randomized clinical trial called the Women's Health Initiative reported that hormone therapy, actually, increased the risk of stroke and cardiovascular disease among postmenopausal women.
The Hormone Therapy Controversy What Makes Reliable Evidence case study solution
Almost overnight, prescriptions for hormone treatment plummeted. For millions of girls who were abruptly taken off hormones or denied therapy, though, the feeling of confusion and anguish stayed. At the heart of the hormone therapy controversy was the undeniable fact that two different research strategies- observational studies and randomized experiments -had arrived at diametrically opposite consequences, once again raising questions about what made up dependable evidence. Instance Amount 2005.0
PUBLICATION DATE: November 13, 2013 PRODUCT #: HKS775-PDF-ENG
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