Medical Assignment Case Solution And Analysis, HBR Case Study Solution & Analysis of Harvard Case Studies

Types of diseases and their features:

Superficial spreading melanoma
Description
Incidence Type of skin cancer occurs in the upper skin area, found in males mostly. 70% diagnosed melanoma.
Typical size range >6mm and less than 1 cm
Shape Starts with mole turned into Thin patch (radial growth),) irregular shape
Colours Light brown, dark brown, black, blue gray and pink.
Surface features Radial growth on epidermis or upper layer of skin.
Features on palpation Irregular surface, dry or warty.
Symptoms Thickening of the part, bleeding, itching and stinging
Differential diagnosis Dermoscopy, skin biopsy and blood tests.
Associations Cutaneous melanoma.
Dermoscopic pattern Growth patterns, invasion of blood, biopsy.
Dermoscopic clues -
Lentigo malgina Description
Incidence Skin cancer, occurs on sun damaged skin, particularly found on nose and cheeks.
Typical size range >6 mm and often several centimeters in diameter.
Shape Irregular shape
Colours Dark brown, pink, red or whitelight, brown or tan.
Surface features Pigmentation.
Features on palpation Smooth surface.
Symptoms Stinging and bleeding, ulceration.
Differential diagnosis Confocal microscopy, biopsy and blood tests.
Medical Assignment Harvard Case Solution & Analysis
Associations
Dermoscopic pattern Granular-annular pattern.
Dermoscopic clues Strawberry pattern.
Nodular melanoma
Description
Incidence Nodular melanoma is more common in males than females. Most are over the age of 50.
Typical size range >6mm up to 1 cm.
Shape Dome shaped, symmetrical firm lump.
Colours Black red or skin color.
Surface features Pigmentation that is often variable.
Features on palpation Warty surface, smooth, rough and crusted also.
Symptoms Elevation, firmness and growth, i.e. nodule shaped growth.
Differential diagnosis Biopsy at the first stage
Diagnosis of primary melanoma
Breslow thickness to the nearest 0.1 mm
Clark level of invasion
Margins of excision i.e. the normal tissue around the tumor
Whether or not there is ulceration
Associations Polypoid melanoma.
Dermoscopic pattern Disorganized asymmetrical structure
Atypical vascular patterns
Blue-grey structures
Multiple colors
Dermoscopic clues Vascular lesions such as angiomas and pyogenic granuloma.

Desmoplastic melanoma
Description
Incidence Usually occurs on white skin individuals, 65% in males as compare to females.
Typical size range >6mm to 1-2 cmm
Shape Scar like. Rounded and irregular
Colours Skin color, often pigmented.
Surface features Exposed Areas of head and neck,
Features on palpation Firm scar-like nodule with a smooth or irregular surface.
Symptoms Thickening of part of the lesion
Increasing number of colors, especially blue or black
Ulceration or bleeding
Itching or stinging
Differential diagnosis Biopsy, blood tests to distinguishing it from other liaisons.
Associations Series of changes of DNA.
Dermoscopic pattern Features of melanocytic lesion.
Asymmetrical structure and colors
Dermoscopic clues Polymorphous vascular pattern and multiple colors.

Acral melanoma
Description
Incidence Common in people having darker skin type. 22-72% in darker skin people. Arises in males and females after the age of 40.
Typical size range >6mm and up to several centimeters.
Shape Irregular
Colours mixture of brown, and blue-grey, black and red colors
Surface features Like a mole,
Features on palpation Thicker surface, dry or warty.
Symptoms Palm, sole or beneath the nail. Ulceration and bleeding.
Differential diagnosis Melanocytic nevus (moles)
Viral warts
Bleeding i.e. sub cornealhemorrhage.
Associations It involves genetic mutations.
Dermoscopic pattern Parallel ridge pattern (PRP).
Dermoscopic clues................

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