Benzodiazepine Case Study Analysis
Overcoming difficulties
The side effects caused by the drug can be reduced by prescribing sufficient dose that does not cause drowsiness, headache and other side effects. The dose for clonazepam, is recommended to be 0.125 mg b.i.d decrements every three days. In addition, flexible dosing depending on the personal needs of the patients should be prescribed by the practicers. (Jeffrey Susman, 2005)
In addition, drugs such as Flumazenil (Romazicon) should be used to reverse the side effects of the benzodiazepine drugs. The Flumazenil drug blocks the actions of benzodiazepines by inhibiting the activity at benzodiazepine receptor sites. The average daily dose that should be taken to reverse the effects of the drug is 0.2 mg IV given over 15 seconds. (Varela, 2020)
Related drugs in the market
The substitutes for the drugs include:
- Sertraline (Zoloft) which is an anti-depressant drug
- Buspirone(BuSpar) used to treat chronic anxiety
- Ramelteon, used to treat insomnia
- Antihistamines, over the counter drugs used as sedatives.
In addition, the common types of benzodiazepine available in the market includes:
- Alprazolam (Xanax) used to treat anxiety and panic attacks
- Librium used to treat anxiety and withdrawal from Alcohol
- Klonopin, used to treat anxiety, insomnia, seizures and panic attacks
- Valium
- Lorazepam (Ativan)
- Dalmane
- Serix
- Restoril
- (Harvard Health Publishing, 2020)
Conclusion
Benzodiazepines is a widely used drug in the USA, used for treating various medical conditions that includes anxiety, insomnia, alcohol withdrawal, controlling seizure, relaxing muscles, given as a sedative before surgeries. The drug affects and target a key endogenous chemical in the brain called GABA which enables neurotransmission.The benzodiazepines ring system comprises of a synthesis between the benzene and diazepam ring systems, which is a heterocycle having two nitrogen atoms, five carbon atom and numerous double bonds. The most common side effects of the drugs include dizziness, unsteadiness, weakness, depression, headache, sleep disturbance, insomnia,aggression, dementia i.e. memory impairment and irritability. Therefore, it was suggested that sufficient dose should be prescribed and Flumazenil (Romazicon) should be used to reverse the side effects of the benzodiazepine drugs...........................
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